Epinephrine (historical) group (N = 18) | Vasopressin (prospective) group (N = 13) | P value | |
---|---|---|---|
Gender: male/female | 14/4 | 10/3 | 0.99 |
Age | 43.2 ± 19.9 (18–83) | 44.9 ± 23.2 | 0.79 |
Location of arrest: public place/home/workplace | 11/2/5 | 8/1/4 | 0.82 |
Mechanism of injury: traffic incident/fall-jump/blow-assault/other | 7/6/3/2 | 6/4/2/1 | 0.78 |
Arrest witnessed: yes/no | 13/5 | 9/4 | 0.99 |
Bystander CPR: yes/no | 7/11 | 3/10 | 0.71 |
Response time: call to start with CPR (min) | 8 ± 5 | 9 ± 4 | 0.93 |
Initial PETCO2 (kPa) | 0.93 ± 0.58 | 0.98 ± 0.49 | 0.89 |
Initial MAP (mmHg) after ROSC | 75.2 ± 12.2 | 94.5 ± 10.2 | < 0.01 |
Resuscitation by medical team (min) | 28.8 ± 8.9 | 18.6 ± 8.1 | < 0.01 |
ROSC (%) | 3/15 (17%) | 11/13 (85%) | < 0.001 |
24-h survival rate (%) | 2/18 (11%) | 8/13 (62%) | 0.001 |
Average volume of resuscitation (without HHS) (ml) | 2,722 ± 951 | 1,744 ± 548 | < 0.01 |
Average dose of epinephrine (mg) | 7.8 ± 3.8 | 4.3 ± 2.7 | < 0.01 |
ISS at admission: median (percentile 25 and 75) | 24 (17, 27) | 23 (16, 26) | 0.95 |
Final MAP at admission (mmHg) | 80.3 ± 12.4 | 100.4 ± 11.4 | < 0.01 |
Final PETCO2 at admission (kPa) | 2.8 ± 0.4 | 4.5 ± 0.9 | < 0.01 |
Discharge alive from hospital | 1/18 (6%) | 4/13 (31%) | 0.13 |