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Table 2 Indications for warfarin treatment in the cohorts treated with either FEIBA or FFP

From: Activated prothrombin complex concentrate factor VIII inhibitor bypassing activity (FEIBA) for the reversal of warfarin-induced coagulopathy

Indication

FEIBA n  = 72

FFP n = 69

INR <5

INR ≥5

total

INR <5

INR ≥5

Total

Atrial fibrillation

61.2%(30)

34.8%(8)

52.8%(38)

38.9%(21)

33.3%(5)

37.7%(26)

Complicated atrial fibrillation

6.1%(3)

8.7%(2)

6.9%(5)

14.8%(8)

13.3%(2)

14.5%(10)

Atherosclerosis

6.1%(3)

21.7%(5)

11.1%(8)

1.2%(1)

20.0%(3)

5.8%(4)

Valve replacement

12.2%(6)

8.7%(2)

11.1%(8)

14.8%(8)

6.7%(1)

13.0%(9)

Thromboembolism

10.2%(5)

21.8%(5)

13.9%(10)

24.1%(13)

26.7%(4)

24.6%(17)

Other

4.1%(2)

4.3%(1)

4.2%(3)

5.6%(3)

0.0%(0)

4.3%(3)

Total

100%(49)

100%(23)

100%(72)

100%(54)

100%(15)

100%(69)

  1. P = 0.511 using chi-square with 5 degrees of freedom comparing the FEIBA group with the FFP group subdivided by indications