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Table 2 Clinical manifestations of serotonin syndrome

From: The serotonin syndrome—the need for physician’s awareness

Autonomic

Hyperthermia, hypertension, tachycardia, sweating, mydriasis flushing

Cognitive

Agitation, confusion, hyperactivity, hypomania

Neuromuscular

Hyperreflexia, hypertonia, clonus, tremor (more prominent in lower limbs)