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Table 3 Sternbach criteria for serotonin syndrome

From: The serotonin syndrome—the need for physician’s awareness

Recent addition or increase in a serotonergic agent

Absence of other possible etiologies like infections, etc.

No recent addition or increase of neuroleptic agent

Three of the following symptoms:

Alteration in mental status (confusion, hypomania)

Agitation

Myoclonus

Hyperreflexia

Sweating

Shivering

Tremor

Diarrhea

Incoordination

Fever