From: Emerging concepts in the diagnosis and treatment of patients with undifferentiated angioedema
Angioedema type | Urine histamine | Serum tryptase | C4 level | C1-INH Level (antigenic) | C1-INHLevel (functional) | C1q level | C3 level |
---|---|---|---|---|---|---|---|
Histamine-mediated angioedema | ↑ | ↑ | NL | NL | NL | NL | NL |
Hereditary angioedema types I and II | NL | NL | ↓ | ↓ (type I) | ↓ | NL | NL |
NL (type II) | |||||||
Hereditary angioedema type III | NL | NL | NL | NL | NL | NL | NL |
Acquired angioedema | NL | NL | ↓ | ↓ or NL | ↓ | ↓ | ↓ or NL |
ACE inhibitor-induced angioedema | NL | NL | NL | NL | NL | NL | NL |
Idiopathic angioedema | NL | NL | NL | NL | NL | NL | NL |
Pseudoallergic angioedema | NL | NL | NL | NL | NL | NL | NL |