| Post-intubation hypotension | Overall adverse event | ||
---|---|---|---|---|
Variable | OR (95% CI) | P Value | OR (95% CI) | P Value |
Primary exposure | ||||
Age ≥ 65 years (vs. < 65 years) | 2.6 (1.3–5.6) | 0.01 | 1.0 (0.8–1.3) | 0.97 |
Age (categorical variable)* | ||||
  Age ≥ 80 years (vs. < 80 years) | 2.4 (1.2–4.8) | 0.01 | 0.98 (0.7–1.4) | 0.92 |
Age, decile (ordinal variable: OR per each incremental decile)* | 1.3 (1.1–1.7) | 0.01 | 0.98 (0.9–1.1) | 0.66 |
Covariate | ||||
Female (vs. male) | 1.1 (0.6–2.2) | 0.75 | 1.5 (1.1–1.9) | 0.009 |
Primary indication | Â | 0.68 | Â | 0.88 |
  Medical | 1.2 (0.5–3.2) |  | 1.0 (0.7–1.5) |  |
  Trauma | 1 [reference] |  | 1 [reference] |  |
Sedative (%) | Â | 0.001 | Â | 0.14 |
  No sedatives | 0.1 (0.01–1.0) |  | 1.2 (0.8–1.7) |  |
  Benzodiazepine | 3.6 (1.3–10.0) |  | 1.5 (1.0–2.3) |  |
  Propofol | 1 [reference] |  | 1 [reference] |  |
  Ketamine | 1.0 (0.1–9.2) |  | 0.9 (0.4–2.2) |  |
  Other†| 5.9 (1.0–31.8) |  | 2.1 (0.9–4.9) |  |
Method | Â | 0.58 | Â | 0.73 |
  RSI | 1.2 (0.6–2.5) |  | 1.1 (0.7–1.6) |  |
  Non-RSI‡ | 1 [reference] |  | 1 [reference] |  |
Multiple attempts§ (vs. 2 or fewer attempts) | (0.4-2.6) | 0.98 | 4.7 (3.4-6.4) | < 0.001 |