Table 1 Cohort characteristics
Total cohort (n= 60) | Group 1 (n= 41) | Group 2 (n= 19) | |
|---|---|---|---|
Male N | 42/60 (70%) | ||
PCC Indication (n) | |||
Intracranial bleeding | 21 (35%) | 21 | 0 |
Gastrointestinal bleeding | 14 (23.3%) | 8 | 6 |
Pre-surgery/intervention | 11 (18.3%) | 6 | 5 |
Intramuscular hematoma | 4 (6.7%) | 0 | 4 |
Postoperative bleeding | 3 (5.0%) | 1 | 2 |
Post-traumatic bleeding | 2 (3.3%) | 2 | 0 |
Pulmonary bleeding | 2 (3.3%) | 1 | 1 |
Pharyngeal bleeding | 1 (1.7%) | 0 | 1 |
Hematuria (unstable patient) | 1 (1.7%) | 1 | 0 |
Bleeding with acute abdominal aneurysm | 1 (1.7%) | 1 | 0 |
Mean age (years) (SD) | 69 (± 12.7) | 70.1 (± 12.4) | 66.8 (± 13.3) |
Mean estimated weight | 80.5 (± 13.7) | 81.5 (± 12.6) | 78.2 (± 15.9) |
Baseline INR | 5.23 (± 2.96) | 4.20 (± 2.13) | 7.44 (± 3.32) |
Mean PCC dose (ml) | |||
Dosing table used | 66.2 (± 22.1) | 74.6 (± 22.5) | 52.5 (± 12.5) |
Dosing table not used | 45.3 (± 19.6) | 48.5 (± 19.1) | 25 (± 7.1) |
Combined | 61.0 (± 23.2) | 66.3 (± 24.6) | 49.5 (± 14.7) |