Blood product transfusion in emergency department patients: a case-control study of practice patterns and impact on outcome

Table 3 Primary and secondary outcomes according to study group

Outcome	Controls: no transfusion in ED group (n = 204)	Cases: transfusion group (n = 204)	Odds ratio or between-group difference (95% CI)	P value*
Primary composite outcome, n (%)	26 (12.7)	28 (13.7)	0.91 (0.48–1.72)	0.77
• Respiratory failure	17 (8.3)	19 (9.3)	1.13 (0.57–2.24)	0.73
• ICU admission	8 (3.9)	7 (3.4)	0.87 (0.31–2.45)	0.79
• ARDS	9 (4.4)	14 (6.9)	1.60 (0.68–3.78)	0.28
Secondary outcomes (days)
Ventilator-free	24.7 (9.4)	23.7 (10.3)	1.0 (−0.9–2.9)	0.30
ICU-free	24.7 (8.3)	23.7 (9.0)	0.9 (−0.8–2.6)	0.30
Hospital-free	20.0 (8.5)	18.6 (9.1)	1.4 (−0.3–3.1)	0.11
RRT, n (%)	18 (8.8)	7 (3.4)	0.37 (0.15–0.90)	0.02
Mortality, n (%)	18 (8.8)	22 (10.8)	1.25 (0.65–2.41)	0.51

The primary outcome was a composite outcome that combined the event rate for respiratory failure, ICU admission, and acute respiratory distress syndrome
*P value for the primary outcome measure was a Wald test estimated using a logistic regression model adjusting for body mass index, sepsis, shock (i.e., vasopressor use), ED mechanical ventilation, and fluid balance
*P values for the secondary outcomes are from the Chi-square test (categorical data) and the independent sample t test (continuous data)
CI confidence interval, ICU intensive care unit, ARDS acute respiratory distress syndrome, RRT renal replacement therapy

ISSN: 1865-1380