Fig. 4
From: Angioedema in the emergency department: a practical guide to differential diagnosis and management
Schematic representation of angioedema attack onset and duration. Histamine-mediated angioedema attacks tend to have rapid onset and resolution. Bradykinin-mediated angioedema usually develops more slowly and can persist for ≤5 days, although angiotensin-converting enzyme inhibitor (ACEi)–induced angioedema will usually resolve ≤48 h once the drug is discontinued