Discharge or admit? Emergency department management of incidental pulmonary embolism in patients with cancer: a retrospective study

Banala, Srinivas R.; Yeung, Sai-Ching Jim; Rice, Terry W.; Reyes-Gibby, Cielito C.; Wu, Carol C.; Todd, Knox H.; Peacock, W. Frank; Alagappan, Kumar

doi:10.1186/s12245-017-0144-9

International Journal of Emergency Medicine

Table 2 Multivariate analysis of factors affecting survival outcomes

From: Discharge or admit? Emergency department management of incidental pulmonary embolism in patients with cancer: a retrospective study

	30-day survival				90-day survival				Overall survival
	P	RR	95% CL for RR		P	RR	95% CL for RR		P	RR	95% CL for RR
	P	RR	Lower	Upper	P	RR	Lower	Upper	P	RR	Lower	Upper
Age	0.272	0.975	0.932	1.020	0.768	0.995	0.962	1.029	0.388	1.009	0.989	1.029
Sex	0.248	0.455	0.120	1.731	0.262	0.623	0.272	1.425	0.431	0.837	0.537	1.304
Race (reference: Black)	0.724				0.858				0.949
Hispanic	0.287	0.383	0.065	2.240	0.684	0.792	0.259	2.428	0.626	1.180	0.607	2.295
Other	0.697	1.532	0.178	13.152	0.485	0.484	0.063	3.704	0.809	0.911	0.430	1.933
Non-Hispanic white	0.972	0.000	0.000	undefined	0.654	0.696	0.143	3.385	0.808	1.129	0.422	3.021
Cancer type (liquid^a vs. solid)	0.955	0.000	0.000	undefined	0.018*	0.042	0.003	0.580	0.016*	0.218	0.063	0.752
Cancer stage (reference: 0)	0.941				0.938				0.004*
I	>0.999	1.154	0.000		0.996	0.000	0.000		0.963	0.000	0.000	undefined
II	0.989	0.000	0.000		0.984	0.000	0.000		0.015	0.085	0.012	0.618
III	0.377	2.364	0.350	15.969	0.980	1.022	0.189	5.512	0.035	0.213	0.050	0.900
IV	0.961	0.000	0.000	undefined	0.375	0.501	0.109	2.306	0.013	0.363	0.163	0.809
ECOG PS (reference: 0)	0.136				0.084				0.020*
1	0.972	0.000	0.000		0.979	0.000	0.000		0.010	0.084	0.013	0.553
2	0.013	0.028	0.002	0.473	0.093	0.145	0.015	1.384	0.190	0.416	0.112	1.543
3	0.079	0.099	0.008	1.308	0.311	0.328	0.038	2.836	0.192	0.427	0.119	1.536
4	0.135	0.106	0.006	2.004	0.824	0.773	0.081	7.419	0.910	1.085	0.263	4.475
Charlson comorbidity index (age unadjusted)	0.025*	0.518	0.291	0.922	0.017*	0.593	0.386	0.911	0.041*	0.766	0.592	0.990
Tachycardia (>100 beats/min)	0.714	0.718	0.122	4.235	0.635	0.761	0.246	2.356	0.804	1.081	0.582	2.008
Hypotension (systolic <100 mmHg)	0.995	103681.952	0.000		0.993	407878.592	0.000		0.710	1.465	0.195	10.983
Tachypnea (>20 breaths/min)	0.058	0.123	0.014	1.075	0.167	0.314	0.061	1.626	0.594	0.723	0.220	2.380
Hypoxemia (oxygen saturation <93%)	0.030*	0.096	0.011	0.800	0.207	0.385	0.088	1.694	0.978	0.987	0.388	2.510
Location of incidental PE (reference: subsegmental)	0.009*				0.083				0.170
Saddle	0.004*	33.513	3.142	357.404	0.023	6.185	1.282	29.828	0.287	1.742	0.627	4.841
Main/lobar pulmonary artery	0.316	2.992	0.351	25.472	0.248	2.199	0.577	8.382	0.688	1.144	0.595	2.199
Segmental	0.713	1.492	0.177	12.549	0.570	1.425	0.420	4.826	0.269	0.736	0.428	1.267

Abbreviations: CL confidence limit, ECOG PS Eastern Cooperative Oncology Group performance status, PE pulmonary embolism, RR relative risk
^aIncludes multiple myeloma, lymphoma, leukemia, stem cell transplant
*Significant at P < 0.05

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