Table 1 Baseline characteristics among septic patients defined by SOFA or SIRS criteria

Female sex, n (%)

195(41.9)

217(54.5)

12.6(6.0–19.2)

Age, median, years (IQR)

74.1(65–83)

71.2(56–80)

4.7(2.6–6.8)

Charlson Comorbidity Index, n

 0

109(23.4)

125(31.4)

8.0(2.0–14.0)

 1–2

232(49.8)

195(49.0)

0.8(÷5.9–7.5)

 3+

125(26.8)

78(19.6)

7.2(1.6–12.8)

Previously admitted with sepsis, n (%)

153(32.8)

110(27.6)

5.2(÷0.9–11.3)

Length of stay, median, days (IQR)

6.7(4.0–10.6)

4.3(2.7–7.0)

1.9(1.3–2.4)

Vital signs on admission, median (IQR)

 Severity of disease

  Total SOFA score

3(2–4)

0(0–1)

–

  Systolic blood pressure, mmHg^a (IQR)

122(106–145)

135(122–150)

12(9–15)

   ≤ 90 mmHg, n(%)

37(7.9)

2 (0.5)

7.4(4.9–10.0)

  Respiratory rate, breaths/min (IQR)

21(18–26)

21 (18–25)

0

  Heart rate, beats/min (IQR)

95(81–112)

102(93–112)

7(4–10)

  Peripheral oxygen saturation, %(IQR)

95(93–97)

96(94–98)

1(1–2)

  Core temperature, °C^b (IQR)

37.7(36.8–38.5)

38.3(37.5–38.8)

0.5(0.3–0.7)

  Glasgow Coma Scale < 15, n (%)

122(30.4)

30(7.5)

22.9(18.0–27.8)

Laboratory variables, median (IQR)

 C-reactive protein (mg/L)

94(36–167)

104(35–174)

3(÷13–7)

 White blood cell count, (× 10⁹/L)

12.4(9.0–17.5)

13.8(10.5–17.3)

1.2(0.5–2.0)

 Creatinine (μmol/L)

111(73–168)

74(61–92)

32(25–39)

 Bilirubin (μmol/L)

11(7–17)

9(6–13)

2(1–2)

 Platelet count (× 10⁹/L)

206(144–280)

256(207–324)

57(45–70)

 Lactate (mmol/L)^c

1.4(0.9–2.2)

1.0(0.7–1.7)

0.3(0.2–0.4)

 Glucose (mmol/L)

7.3(6.1–8.9)

6.7(6.0–8.1)

0.4(0.1–0.6)

Admission to ICU, n (%)

73(15.7)

20(5.0)

10.7(6.7–14.6)

 Vasopressor therapy, n (%)

14(3.0)

3(0.8)

2.2(0.4–4.0)

 Ventilation therapy, n (%)

28(6.0)

7(1.8)

4.2(1.7–6.7)

 Dialysis treatment, n (%)

3(0.6)

1(0.3)

0.3(÷0.5–1.2)