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Table 3 Comparison of outcomes between spectrum in appropriate antibiotics and inappropriate spectrum antibiotics groups

From: Effect of appropriate dose, spectrum, and timing of antibiotics on 28-day mortality in patients with sepsis in the emergency department

  Appropriate antibiotics spectrum, N=489 Inappropriate antibiotics spectrum, N=104 Adjusted odds ratioa
Adjusted coefficientb:
Appropriate antibiotics
P value
28-day mortality, n (%) 14 (2.9%) 9 (8.78%) 0.38 (0.15, 0.99) a 0.047
In-hospital mortality, n (%) 21 (4.3%) 15 (14.4%) 0.28 (0.13, 0.61) a 0.001
28-day ventilator- free days, mean ± SD 26.77±4.46 23.75±8.73 0.06** (0.01, 0.11) b 0.01
28-day hospital-free days, mean ± SD 21.27±8.08 16.90±10.48 0.10** (− 0.00, 0.21) b 0.06
  1. aAdjusted odds ratio (95% confidence interval): qSOFA, respiratory rate, oxygen saturation
  2. bApply log transformation for fitting model to normal distribution before adjusted coefficient (mean difference): qSOFA, respiratory rate, oxygen saturation. After we did a log transform, 16 data of 28-day ventilator free day and 57 data of 28-day hospital free day were missing because log [0] transformed to infinities. We had completed case analysis as 577 patients for 28-day ventilator free day and 536 patients 28-day hospital free day outcomes
  3. SD standard deviation, qSOFA quick Sequential Organ Failure Assessment