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Table 2 Time management in sepsis bundles and 28-day mortality using sepsis-3 and REWs

From: The Ramathibodi early warning score as a sepsis screening tool does not reduce the timing of antibiotic administration

Outcomes

Sepsis-3 (N= 303)

REWs (N= 176)

p-value

Primary outcomes

Administration of antibiotics within 1 h,N(%)

186 (61.4%)

140 (79.5%)

< 0.001

Time from presentation to administration of antibiotics (minutes), median (IQR)

50 (46–56)

45 (41–50)

0.112

Secondary outcomes

ICU admission,N(%)

45 (14.8%)

42 (23.9%)

0.014

Time to ICU admission (hours), median (IQR)

20 (14–15)

11 (7–14)

0.007

28-day mortality,N(%)

26 (8.6%)

12 (6.8%)

0.491

Propensity matching

Sepsis-3 (N= 153)

REWs (N= 153)

p-value

Primary outcome

Administration of antibiotics within 1 h,N(%)

123 (80.4%)

122 (79.7%)

0.886

Time from presentation to administration of antibiotics (minutes), median (IQR)

35 (33–38)

45 (41–52)

< 0.001

Secondary outcomes

ICU admission,N(%)

28 (18.3%)

34 (22.2%)

0.393

Time to ICU admission (hours), median (IQR)

23 (16–32)

10 (6–14)

0.006

28-day mortality,N(%)

14 (9.2%)

10 (6.5%)

0.671

  1. REWs Ramathibodi early warning score, IQR Interquartile range, ICU Intensive care unit