Table 2 Time management in sepsis bundles and 28-day mortality using sepsis-3 and REWs
Outcomes | Sepsis-3 (N= 303) | REWs (N= 176) | p-value |
Primary outcomes | |||
 Administration of antibiotics within 1 h,N(%) | 186 (61.4%) | 140 (79.5%) | < 0.001 |
 Time from presentation to administration of antibiotics (minutes), median (IQR) | 50 (46–56) | 45 (41–50) | 0.112 |
Secondary outcomes | |||
 ICU admission,N(%) | 45 (14.8%) | 42 (23.9%) | 0.014 |
 Time to ICU admission (hours), median (IQR) | 20 (14–15) | 11 (7–14) | 0.007 |
 28-day mortality,N(%) | 26 (8.6%) | 12 (6.8%) | 0.491 |
Propensity matching | Sepsis-3 (N= 153) | REWs (N= 153) | p-value |
Primary outcome | |||
 Administration of antibiotics within 1 h,N(%) | 123 (80.4%) | 122 (79.7%) | 0.886 |
 Time from presentation to administration of antibiotics (minutes), median (IQR) | 35 (33–38) | 45 (41–52) | < 0.001 |
Secondary outcomes | |||
 ICU admission,N(%) | 28 (18.3%) | 34 (22.2%) | 0.393 |
 Time to ICU admission (hours), median (IQR) | 23 (16–32) | 10 (6–14) | 0.006 |
 28-day mortality,N(%) | 14 (9.2%) | 10 (6.5%) | 0.671 |