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Table 2 Time management in sepsis bundles and 28-day mortality using sepsis-3 and REWs

From: The Ramathibodi early warning score as a sepsis screening tool does not reduce the timing of antibiotic administration

Outcomes Sepsis-3 (N= 303) REWs (N= 176) p-value
Primary outcomes
Administration of antibiotics within 1 h,N(%) 186 (61.4%) 140 (79.5%) < 0.001
Time from presentation to administration of antibiotics (minutes), median (IQR) 50 (46–56) 45 (41–50) 0.112
Secondary outcomes
ICU admission,N(%) 45 (14.8%) 42 (23.9%) 0.014
Time to ICU admission (hours), median (IQR) 20 (14–15) 11 (7–14) 0.007
28-day mortality,N(%) 26 (8.6%) 12 (6.8%) 0.491
Propensity matching Sepsis-3 (N= 153) REWs (N= 153) p-value
Primary outcome
Administration of antibiotics within 1 h,N(%) 123 (80.4%) 122 (79.7%) 0.886
Time from presentation to administration of antibiotics (minutes), median (IQR) 35 (33–38) 45 (41–52) < 0.001
Secondary outcomes
ICU admission,N(%) 28 (18.3%) 34 (22.2%) 0.393
Time to ICU admission (hours), median (IQR) 23 (16–32) 10 (6–14) 0.006
28-day mortality,N(%) 14 (9.2%) 10 (6.5%) 0.671
  1. REWs Ramathibodi early warning score, IQR Interquartile range, ICU Intensive care unit