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Table 3 Impact of time of antibiotic administration on 28-day mortality in patients with sepsis

From: The Ramathibodi early warning score as a sepsis screening tool does not reduce the timing of antibiotic administration

Time to antibiotic administration

HR (95% CI)

P-value

Probability

aHRa (95% CI)

P-value

< 1 h

Reference

 

7.36

Reference

 

1 to 3 h

1.28 (0.55–3.00)

0.571

7.64

1.95 (0.86–4.57)

0.115

> 3 h

6.41 (1.86–22.13)

0.003

33.33

7.04 (1.45–34.11)

0.015

  1. HR Hazard ratio, CI Confidence interval, aHR Adjusted hazard ratio
  2. aAdjusted for blood lactate level ≥ 2 mmol/L, systolic blood pressure < 90 mmHg, SpO2 < 94%, mental status change, and ICU admission