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Table 3 Impact of time of antibiotic administration on 28-day mortality in patients with sepsis

From: The Ramathibodi early warning score as a sepsis screening tool does not reduce the timing of antibiotic administration

Time to antibiotic administration HR (95% CI) P-value Probability aHRa (95% CI) P-value
< 1 h Reference   7.36 Reference  
1 to 3 h 1.28 (0.55–3.00) 0.571 7.64 1.95 (0.86–4.57) 0.115
> 3 h 6.41 (1.86–22.13) 0.003 33.33 7.04 (1.45–34.11) 0.015
  1. HR Hazard ratio, CI Confidence interval, aHR Adjusted hazard ratio
  2. aAdjusted for blood lactate level ≥ 2 mmol/L, systolic blood pressure < 90 mmHg, SpO2 < 94%, mental status change, and ICU admission