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Table 1 Baseline characteristics and bivariate analysis by mortality

From: Clinical characteristics and mortality associated with COVID-19 at high altitude: a cohort of 5161 patients in Bogotá, Colombia

Variable

Overall patients (n = 5161)

Alive (n = 3856)

Death (n = 1305)

p-value

Patients

Missing (n)

Patients

Missing (n)

Patients

Missing (n)

 

Demographic

 Age median (IQR)

66 (53–77)

0

62 (48–73)

0

76 (67–84)

0

< 0.01*

 Days of hospital stay (IQR)

8 (4–13)

0

7 (3–12)

3356

11 (5–17)

655

< 0.01*

 Days of ICU (IQR)

9 (4–15)

3951

8 (4–14.5)

3313

9 (5–15)

638

0.016*

 Body mass index median (IQR)

26.34 (23.46–29.38)

3

26.44 (23.71–29.41)

2

25.84 (23.18–29.35)

1

< 0.01*

Sex

 Female

2340 (45.34%)

0

1850 (79.06%)

0

490 (20.94%)

0

< 0.01*

 Male

2821 (54.65%)

0

2006 (71.11%)

0

815 (28.89%)

0

< 0.01*

Management site

 Inpatient

2970 (57.54%)

0

2459 (82.79%)

0

511 (17.21%)

0

< 0.01*

 ICU

1223 (23.69%)

0

543 (44.40%)

0

680 (55.60%)

0

< 0.01*

 Outpatient

854 (16.54%)

0

854 (100.00%)

0

0 (0%)

0

< 0.01*

 Emergency

114 (2.20%)

0

0 (0%)

0

114 (100%)

0

< 0.01*

Comorbidities

 Hypertension

1171 (22.68%)

0

803 (68.57%)

0

368 (31.43%)

0

< 0.01*

 Diabetes types 1 and 2

256 (4.96%)

0

163 (63.67%)

0

93 (36.33%)

0

< 0.01*

 COPD

290 (5.61%)

0

158 (54.48%)

0

132 (45.52%)

0

< 0.01*

 HIV

9 (0.17%)

0

7 (77.78%)

0

2 (22.22%)

0

-

 Hypothyroidism

358 (6.93%)

0

247 (68.99%)

0

111 (31.01%)

0

0.011*

Laboratory values median (IQR)

 Leukocyte blood count

7,985 (0.2–262.9)

439

7.75 (5.76–10.51)

415

8.62 (6.22–12.02)

24

< 0.01*

 Neutrophil-lymphocyte ratio

6,0303 (3,4258–10,7008)

442

5.391 (3.131–9.519)

415

8,322 (4,634–14,896)

27

< 0.01*

 Haematocrit

43.4 (39.2–47)

434

43.7 (39.9–47.1)

410

42.5 (36.9–46.7)

24

< 0.01*

 Haemoglobin

14.5 (13–15.8)

433

14.6 (13.3–15.8)

410

14.1 (12.2–15,675)

23

< 0.01*

 LDH

337 (255–445)

765

321 (247–410)

661

400 (288–549)

104

< 0.01*

 D-Dimer

950 (540–1802.25)

1013

857 (497–1490)

855

1296 (721.5–2641.5)

158

< 0.01*

 Procalcitonin

0.31 (0.12–1.01)

3592

0.2 (0.09–0.57)

2918

0.63 (0.24–2,225)

674

< 0.01*

 Ferritin

881 (478–1612.5)

4834

789.5 (417.75–1422,25)

3642

1225 (594–2359)

1192

< 0.01*

Oxygenation values median (IQR)

 S/F ratio at admission

339.28 (310.71–423.80)

166

346,429 (321,429–428,571)

159

318,452 (184–361,905)

7

< 0.01*

 S/F ratio at 48 h

325 (254.28–341.52)

806

328,571 (303,333–342,857)

690

281.25 (167,273–328,571)

116

< 0.01*

 P/F ratio at admission

233,3854 (180,9524–274,6429)

711

242,381 (202.5–279,524)

655

191,786 (112.8–254,643)

56

< 0.01*

 S/F ratio at ICU admission

168 (105.55–255.55)

*4011

186 (121.25–288,281)

3356

149,615 (95,667–194)

655

< 0.01*

 P/F ratio at ICU admission

118.14 (81.55–171.44)

*4049

137.4 (91,089–198,917)

3378

105 (76,706–146)

671

< 0.01*

  1. ICU intensive care unit, COPD chronic obstructive pulmonary disease, HIV human immunodeficiency virus, LDH lactate dehydrogenase, S/F oxygen saturation to fraction inspired oxygen, P/F partial pressure of oxygen to fraction inspired oxygen
  2. *P-value refers to statistically significant result