Skip to main content

Table 1 Baseline characteristics and bivariate analysis by mortality

From: Clinical characteristics and mortality associated with COVID-19 at high altitude: a cohort of 5161 patients in Bogotá, Colombia

Variable Overall patients (n = 5161) Alive (n = 3856) Death (n = 1305) p-value
Patients Missing (n) Patients Missing (n) Patients Missing (n)  
Demographic
 Age median (IQR) 66 (53–77) 0 62 (48–73) 0 76 (67–84) 0 < 0.01*
 Days of hospital stay (IQR) 8 (4–13) 0 7 (3–12) 3356 11 (5–17) 655 < 0.01*
 Days of ICU (IQR) 9 (4–15) 3951 8 (4–14.5) 3313 9 (5–15) 638 0.016*
 Body mass index median (IQR) 26.34 (23.46–29.38) 3 26.44 (23.71–29.41) 2 25.84 (23.18–29.35) 1 < 0.01*
Sex
 Female 2340 (45.34%) 0 1850 (79.06%) 0 490 (20.94%) 0 < 0.01*
 Male 2821 (54.65%) 0 2006 (71.11%) 0 815 (28.89%) 0 < 0.01*
Management site
 Inpatient 2970 (57.54%) 0 2459 (82.79%) 0 511 (17.21%) 0 < 0.01*
 ICU 1223 (23.69%) 0 543 (44.40%) 0 680 (55.60%) 0 < 0.01*
 Outpatient 854 (16.54%) 0 854 (100.00%) 0 0 (0%) 0 < 0.01*
 Emergency 114 (2.20%) 0 0 (0%) 0 114 (100%) 0 < 0.01*
Comorbidities
 Hypertension 1171 (22.68%) 0 803 (68.57%) 0 368 (31.43%) 0 < 0.01*
 Diabetes types 1 and 2 256 (4.96%) 0 163 (63.67%) 0 93 (36.33%) 0 < 0.01*
 COPD 290 (5.61%) 0 158 (54.48%) 0 132 (45.52%) 0 < 0.01*
 HIV 9 (0.17%) 0 7 (77.78%) 0 2 (22.22%) 0 -
 Hypothyroidism 358 (6.93%) 0 247 (68.99%) 0 111 (31.01%) 0 0.011*
Laboratory values median (IQR)
 Leukocyte blood count 7,985 (0.2–262.9) 439 7.75 (5.76–10.51) 415 8.62 (6.22–12.02) 24 < 0.01*
 Neutrophil-lymphocyte ratio 6,0303 (3,4258–10,7008) 442 5.391 (3.131–9.519) 415 8,322 (4,634–14,896) 27 < 0.01*
 Haematocrit 43.4 (39.2–47) 434 43.7 (39.9–47.1) 410 42.5 (36.9–46.7) 24 < 0.01*
 Haemoglobin 14.5 (13–15.8) 433 14.6 (13.3–15.8) 410 14.1 (12.2–15,675) 23 < 0.01*
 LDH 337 (255–445) 765 321 (247–410) 661 400 (288–549) 104 < 0.01*
 D-Dimer 950 (540–1802.25) 1013 857 (497–1490) 855 1296 (721.5–2641.5) 158 < 0.01*
 Procalcitonin 0.31 (0.12–1.01) 3592 0.2 (0.09–0.57) 2918 0.63 (0.24–2,225) 674 < 0.01*
 Ferritin 881 (478–1612.5) 4834 789.5 (417.75–1422,25) 3642 1225 (594–2359) 1192 < 0.01*
Oxygenation values median (IQR)
 S/F ratio at admission 339.28 (310.71–423.80) 166 346,429 (321,429–428,571) 159 318,452 (184–361,905) 7 < 0.01*
 S/F ratio at 48 h 325 (254.28–341.52) 806 328,571 (303,333–342,857) 690 281.25 (167,273–328,571) 116 < 0.01*
 P/F ratio at admission 233,3854 (180,9524–274,6429) 711 242,381 (202.5–279,524) 655 191,786 (112.8–254,643) 56 < 0.01*
 S/F ratio at ICU admission 168 (105.55–255.55) *4011 186 (121.25–288,281) 3356 149,615 (95,667–194) 655 < 0.01*
 P/F ratio at ICU admission 118.14 (81.55–171.44) *4049 137.4 (91,089–198,917) 3378 105 (76,706–146) 671 < 0.01*
  1. ICU intensive care unit, COPD chronic obstructive pulmonary disease, HIV human immunodeficiency virus, LDH lactate dehydrogenase, S/F oxygen saturation to fraction inspired oxygen, P/F partial pressure of oxygen to fraction inspired oxygen
  2. *P-value refers to statistically significant result