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Table 2 Bivariate analysis by management site

From: Clinical characteristics and mortality associated with COVID-19 at high altitude: a cohort of 5161 patients in Bogotá, Colombia

Variable

Overall (n = 5161)

Outpatient (n = 854)

Inpatient (n = 2970)

Emergency room (n = 114)

ICU (n = 1223)

p-value

Median (IQ)

Median (IQ)

Missing (n)

Median (IQ)

Missing (n)

Median (IQ)

Missing (n)

Median (IQ)

Missing (n)

 

Demographic

 Age median (IQR)

66 (53–77)

47 (31–64.7)

0

68 (56–79)

0

81 (71–85.7)

0

69 (59–76)

0

< 0.01*

 Days of hospital stay (IQR)

8 (4–13)

1 (0–2)

0

7 (5–11)

0

6 (1–14)

0

15 (10–24)

0

< 0.01*

 Days of ICU (IQR)

-

-

-

-

-

-

-

9 (4–15)

 

-

 Body mass index median (IQR)

26.34 (23.4–29.38)

25.7 (23.3–28.8)

2

26.15 (23.4–28.8)

0

23.7 (23–29.3)

1

27 (24.2–30.8)

0

< 0.01*

Sex

 Female

2340 (45.34%)

489 (20%)

-

1370 (58%)

-

42 (1.7%)

-

439 (18%)

-

< 0.01*

 Male

2821 (54.65%)

365 (12%)

-

1600 (56%)

-

72 (2.5%)

-

784 (27%)

-

< 0.01*

Comorbidities

 Hypertension

1171 (22.68%)

82 (7.0%)

-

723 (61%)

-

27 (2.3%)

-

339 (28%)

-

< 0.01*

 HIV

9 (0.17%)

1 (11%)

-

7 (77%)

-

0 (0%)

-

1 (11%)

-

-

 COPD

290 (5.61%)

21 (7.2%)

-

179 (61%)

-

14 (4.8%)

-

76 (26%)

-

< 0.01*

 Diabetes types 1 and 2

256 (4.96%)

25 (0.04%)

-

138 (0.2%)

-

10 (0.01%)

-

83 (0.1%)

-

< 0.01*

Laboratory values (IQR)

 Leukocyte blood count

7,985 (0.2–262.9)

6.72 (5.23–9.11)

387

7.74 (5.72–10.42)

33

8.31 (5.99–11.82)

17

9.18 (6.68–12.9)

2

< 0.01*

 Neutrophil-lymphocyte ratio

6,0303 (3,4258–10,7008)

3.84 (2.3–6.68)

387

5.54 (3.2–9.71)

35

9.1 (5.7–17.63)

17

8.52 (4.8–14.74)

3

< 0.01*

 Haematocrit

43.4 (39.2–47)

44.1 (41–47.3)

386

43.2 (39–46.8)

29

42.1 (36–45.7)

17

43.7 (39.2–47.4)

2

< 0.01*

 Haemoglobin

14.5 (13–15.8)

14.7 (13.7–15.9)

386

14.4 (12.9–15.7)

28

14.1 (11.6–15.3)

17

14.6 (13–15.9)

2

< 0.01*

 D-Dimer

950 (540–1802.25)

755 (430–1253)

518

914 (530–1703)

347

1506 (962.7–3420.2)

24

1078 (585–2071)

124

< 0.01*

 LDH

337 (255–445)

293 (217–361.75)

448

318 (246–406)

218

429 (283.5–580.5)

23

420 (311–554.5)

76

< 0.01*

 Ferritin

881 (478–1612.5)

825 (615–1680)

817

786 (400–1492)

2765

1415 (826.5–1690)

106

1162 (705–2027)

1146

< 0.04*

 Procalcitonin

0.31 (0.12–1.01)

0.2 (0.08–0.54)

794

0.17 (0.09–0.53)

2288

0.57 (0.21–3.95)

79

0.49 (0.19–1.7)

431

< 0.01*

Outcome

 Alive

3856 (74%)

854 (22%)

-

2459 (63%)

-

0 (0%)

-

543 (14%)

-

< 0.01*

 Dead

1305 (25%)

0 (0%)

-

511 (39%)

-

114 (8.7%)

-

680 (52%)

-

< 0.01*

Oxygenation indices (IQR)

 S/F ratio at admission

339.28 (310.71–423.80)

433.3 (357.4–447.6)

159

339.2 (321.4–414.2)

0

278 (138.5–335.7)

5

321.4 (188–371.4)

2

< 0.01*

 S/F ratio at 48 h

325 (254.28–341.52)

328.5 (293–328.5)

617

328.5 (314.2–346.4)

113

268.7 (170–325)

41

240.8 (156.6–325)

35

< 0.01*

 P/F ratio at admission

233,3854 (180,9524–274,6429)

256 (216.7–293.2)

488

243.3 (203.8–279.5)

192

175.5 (92–227.7)

20

188.9 (106.8–247.6)

11

< 0.01*

 S/F ratio at ICU admission

-

-

-

-

-

-

-

168.5 (105.5–255.5)

73

-

 P/F ratio at ICU admission

-

-

-

-

-

-

-

118.14 (81.5–171.4)

111

-

  1. ICU intensive care unit, COPD chronic obstructive pulmonary disease, HIV human immunodeficiency virus, LDH lactate dehydrogenase, S/F oxygen saturation to fraction inspired oxygen, P/F partial pressure of oxygen to fraction inspired oxygen
  2. *P-value refers to statistically significant result
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