Table 3 Bivariate analysis for invasive mechanical ventilation
Variable | Overall (n = 5161) | No requirement of invasive mechanical ventilation (n = 4263) | Missing (n) | Invasive mechanical ventilation (n = 898) | Missing (n) | p-value |
|---|---|---|---|---|---|---|
Demographic | ||||||
Age median (IQR) | 66 (53–77) | 65 (51–78) | 0 | 68 (59–75) | 0 | < 0.01* |
Days of ICU (IQR) | 4 (2–7) | 3891 | 11 (7–18) | 60 | < 0.01* | |
Days of hospital stay (IQR) | 8 (4–13) | 7 (3–11) | 0 | 16 (10–25) | 0 | < 0.01* |
Body mass index median (IQ) | 26.34 (23.4–29.38) | 26.1 (23.4–29.2) | 3 | 27.3 (24.3–31.1) | 0 | < 0.01* |
Sex | ||||||
Female | 2340 (45.34%) | 2036 (87%) | - | 304 (12%) | - | < 0.01* |
Male | 2821 (54.65%) | 2227 (78%) | - | 594 (21%) | - | < 0.01* |
Management site | ||||||
Outpatient | 854 (16.54%) | 854 (100%) | - | 0 (0%) | - | - |
Inpatient | 2970 (57.54%) | 2962 (99%) | - | 8 (0.002%) | - | - |
Emergency | 114 (2.20%) | 75 (65%) | - | 39 (34%) | - | - |
ICU | 1223 (23.69%) | 372 (30%) | - | 851 (70%) | - | - |
Outcome | ||||||
Alive | 3856 (75%) | 3571 (92%) | - | 285 (0.7%) | - | < 0.01* |
Dead | 1305 (25%) | 692 (53%) | - | 613 (46%) | - | < 0.01* |
Comorbidities | ||||||
Hypertension | 1171 (22.68%) | 935 (79%) | - | 236 (20%) | - | < 0.01* |
HIV | 9 (0.17%) | 8 (88%) | - | 1 (11%) | - | - |
COPD | 290 (5.61%) | 232 (8%) | - | 58 (2%) | - | - |
Diabetes mellitus | 256 (4.96%) | 193 (0.37%) | - | 63 (0.12%) | - | < 0.01* |
Laboratory values (IQR) | ||||||
Leukocyte blood count | 7,985 (0.2–262.9) | 7.7 (5.72–10.49) | 432 | 9.27 (6.7–12.95) | 7 | < 0.01* |
Neutrophil-lymphocyte ratio | 6,0303 (3,4258–10,7008) | 5,436 (3,168–9,674) | 434 | 9,378 (5,399–16,548) | 8 | < 0.01* |
Haematocrit | 43.4 (39.2–47) | 43.3 (39.2–46.9) | 427 | 43.9 (39.4–47.5) | 7 | < 0.01* |
Haemoglobin | 14.5 (13–15.8) | 14.4 (13–15.7) | 426 | 14.7 (13.1–16) | 7 | < 0.01* |
LDH | 337 (255–445) | 317 (243–407) | 725 | 453.5 (341–590) | 40 | < 0.01* |
D-Dimer | 950 (540–1802.25) | 920 (523.2–1711.5) | 937 | 1093 (600–2028) | 76 | < 0.01* |
Procalcitonin | 0.31 (0.12–1.01) | 0.2 (0.09–0.58) | 3347 | 0.58 (0.23–1.92) | 245 | < 0.01* |
Ferritin | 881 (478–1612.5) | 816 (462–1538) | 4002 | 1244 (79.7–1925.7) | 832 | < 0.01* |
Oxygenation indices (IQR) | ||||||
S/F ratio at admission | 339.28 (310.71–423.80) | 342,857 (321.4–428.57) | 163 | 300 (161–347) | 3 | < 0.01* |
S/F ratio at 48 h | 325 (254.28–341.52) | 328.57 (307.1–346.4) | 777 | 202.2(145–317) | 29 | < 0.01* |
P/F ratio at admission | 233,3854 (180,9524–274,6429) | 243.21 (200.4–281) | 777 | 171.4 (98.2–231.4) | 29 | < 0.01* |
S/F ratio at ICU admission | 278.1 (156.6–332.1) | 3942 | 150 (96–192) | 69 | < 0.01* | |
P/F ratio at ICU admission | 154.5 (91–244.9) | 3973 | 112.6 (79.9–150.5) | 76 | < 0.01* | |