Table 2 Performance measures of MTS, SIRS-based, and combined screening system
Test characteristic | MTS category possible sepsis | 95% CI | SIRS-based system | Â | MTS plus SIRS-based system | 95% CI |
|---|---|---|---|---|---|---|
Sensitivity | 47.6% | 40.3 to 55.0% | 51.9% | 44.5% to 59.2% | 64.0% | 56.7 to 70.9% |
Specificity | 99.4% | 99.3 to 99.5% | 97.0% | 96.8% to 97.2% | 96.8% | 96.6 to 97.0% |
AUC | 0.74 | 0.73 to 0.74 | 0.74 | 0.74 to 0.75 | 0.80 | 0.80 to 0.81 |
Positive likelihood ratio | 74.6 | 60.5 to 92.0 | 17.6 | 15.0 to 20.4 | 20.1 | 17.7 to 22.7 |
Negative likelihood ratio | 0.53 | 0.4 to 0.6 | 0.50 | 0.43 to 0.58 | 0.37 | 0.31 to 0.46 |
Positive predictive value | 33.5% | 29.0 to 38.3% | 10.5% | 9.2 to 12.1 | 11.9% | 10.7 to 13.3% |
Negative predictive value | 99.7% | 99.6 to 99.7% | 99.7% | 99.6 to 99.7% | 99.8% | 99.7 to 99.8% |
Accuracy | 99.0% | 99.0 to 99.1% | 96.7% | 96.5 to 96.9% | 96.6% | 96.4 to 96.8% |