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Table 3 Useful steps in managing patients with toxicities from dietary supplements or herbal medicines

From: Dietary supplements and herbal medicine toxicities—when to anticipate them and how to manage them

1. Ask specifically regarding use of such products

2. Secure sample for identification

 

a. Actual herbs or product used

 

b. Prescription or packaging

3. Laboratory studies

 

a. Basic blood count, renal function, liver function, and electrocardiogram

 

b. Heavy metal screening if suspected or if symptoms are non-specific

 

c. Analysis methods exist for some herbal toxins only—colchicines (HPLC, GCMS), tropane alkaloids (GCMS, oxalate (GCMS), vinca alkaloids (HPLC), cardioactive steroids (immunoassay)—check with local laboratory

4. Good resuscitative, symptomatic, and supportive care

5. Use antidote if appropriate

6. Instruct patients and family to stop using the product

7. Consider outpatient monitoring of renal function, liver function, and blood counts

8. Report case to regulating authority

9. Report unusual cases in the medical literature