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Table 3 Indication for the reversal of warfarin effects with FEIBA and FFP

From: Activated prothrombin complex concentrate factor VIII inhibitor bypassing activity (FEIBA) for the reversal of warfarin-induced coagulopathy

Indication

FEIBA n = 72

FFP n = 69

INR <5

INR ≥5

Total

INR <5

INR ≥5

Total

GI bleeding

18.4%(9)

34.8%(8)

23.6%(17)

24.1%(13)

33.3%(5)

26.1%(18)

Intracranial hemorrhage

46.9%(23)

21.7%(5)

38.9%(28)

9.3% (5)

26.7%(4)

13.0% (9)

Preoperative

18.4%(9)

4.3%(1)

13.9%(10)

46.3%(25)

6/7%(1)

37.8%(26)

Other

16.3%(8)

39.1%(9)

23.6%(17)

20.4%(11)

33.3%(5)

23.2%(16)

Total

100%(49)

100%(23)

100%(72)

100% (54)

100%(15)

100% (69)

  1. P = 0.025 using chi-square with 3 degrees of freedom comparing the FEIBA group with the FFP group subdivided by indication