Table 4 Sensitivity analysis: EDLIPS performance at different cutoff points ( n = 2,361)
| Â | EDLIPS cutoff points | ||
|---|---|---|---|
EDLIPS performance | ≥5* | ≥4 | ≥6 |
Prevalence of ALI/ARDS (95% CI) | 0.075 (0.065, 0.086) | 0.075 (0.065, 0.086) | 0.075 (0.065, 0.086) |
Sensitivity (95% CI) | 0.716 (0.643, 0.781) | 0.852 (0.791, 0.901) | 0.557 (0.480, 0.632) |
Specificity (95% CI) | 0.738 (0.719, 0.757) | 0.592 (0.571, 0.613) | 0.848 (0.832, 0.862) |
Positive predictive value | 0.181 (0.153, 0.211) | 0.144 (0.123, 0.167) | 0.227 (0.189, 0.270) |
Negative predictive value | 0.970 (0.961, 0.978) | 0.980 (0.971, 0.987) | 0.960 (0.950, 0.968) |
Likelihood ratio (+)(95% CI) | 2.735 (2.434, 3.073) | 2.088 (1.928, 2.261) | 3.654 (3.099, 4.308) |
Likelihood ratio (−)(95% CI) | 0.385 (0.304, 0.487) | 0.250 (0.175, 0.357) | 0.523 (0.443, 0.618) |
C-statistic (95% CI) | 0.727 (0.692, 0.762) | 0.722 (0.694, 0.750) | 0.702 (0.748, 0.820) |