Table 2 Univariate and multivariate analysis of factors related to 100% compliance with the in the ED attainable goals of the resuscitation bundle of the “Surviving Sepsis Campaign”
Variable | 6 goals | <6 goals | P univariate | Corrected OR (95% CI) multivariate |
|---|---|---|---|---|
No. (%) | 77 (24) | 246 (76) | ||
Patient-related factors | ||||
Age | 62 ± 17 | 68 ± 17 | 0.005 | 0.98 (0.95–1.00)* |
Male sex | 48 (62) | 135 (55) | 0.29 | |
Clinical signs | ||||
Respiratory difficulty (28) | 49 (64) | 114 (46) | 0.006 | 3.38 (1.08–10.64) |
Hypotension <90 mmHg (2) | 37 (48) | 84 (34) | 0.043 | 2.37 (1.07–5.23) |
Altered mental status (15) | 42 (55) | 76 (31) | <0.001 | 4.18 (1.92–9.09) |
Febrile chills (30) | 25 (32) | 47 (19) | 0.016 | |
Laboratory findings | ||||
Lactate >4 (58) | 26 (34) | 74 (30) | 0.41 | |
Urea >7.14 mmol/l (4) | 50 (65) | 184 (75) | 0.102 | |
Thrombocytopenia (8) | 23 (30) | 44 (18) | 0.036 | |
Illness severity | ||||
Total PIRO score | 12.9 ± 4.7 | 12.0 ± 4.9 | 0.149 | |
Total MEDS score | 9.1 ± 3.8 | 8.7 ± 4.1 | 0.447 | |
Institution-related factors | ||||
Academic (as opposed to urban) | 46 (60) | 58 (24) | <0.001 | 3.16 (1.44–6.94)# |
Time of ED presentation: | ||||
8.00 a.m.–23.30 p.m. | 58 (75) | 173 (70) | ||
23.30 p.m.–8.00 a.m. | 19 (25) | 73 (30) | 0.648 | |
Physician-related factors | ||||
ED physician involved (19) | 28 (36) | 52 (21) | 0.01 | |
Admitting specialty | ||||
Medical (the rest being surgical) | 72 (94) | 232 (94) | 0.776 |