Table 1 Patients’ characteristics
Total cohort N = 2659 | < 70 years N = 1678 | ≥ 70 years N = 981 | p value | |
|---|---|---|---|---|
Patient demographics | ||||
Age, mean (SD) | 62.1 (17.1) | 52.5 (13.6) | 78.7 (6.3) | 0,000 |
Sex, n (%) | ||||
Female | 1143 (43.0) | 766 (45.6) | 377 (38.4) | 0.000 |
Male | 1516 (57.0) | 912 (54.4) | 604 (61.6) | |
Comorbidities, n (%) | ||||
COPD (2) | 416 (15.6) | 185 (11.0) | 231 (23.5) | 0.000 |
Heart disease (1) | 432 (16.1) | 156 (9.3) | 276 (28.1) | 0.000 |
Kidney disease (1) | 494 (18.5) | 282 (16.8) | 212 (21.6) | 0.002 |
Liver disease | 125 (4.7) | 102 (6.1) | 23 (2.3) | 0.000 |
Malignancy | 280 (10.5) | 173 (10.3) | 107 (10.9) | 0.628 |
Metastatic malignancy | 37 (13.9) | 256 (15.3) | 117 (11.9) | 0.017 |
Triage category (2), n (%) | 0.174 | |||
Blue | 2 (0.1) | 0 | 2 (0.2) | |
Green | 7 (0.3) | 5 (0.3) | 2 (0.2) | |
Yellow | 1233 (46.4) | 780 (46.5) | 453 (46.2) | |
Orange | 1365 (51.3) | 866 (51.6) | 499 (50.9) | |
Red | 50 (1.9) | 26 (1.5) | 24 (2.4) | |
Suspected site of infection, n (%) | ||||
Lungs | 1319 (49.3%) | 736 (43.9) | 583 (59.4) | 0.000 |
Urogenital tract | 797 (29.8) | 453 (27.0) | 344 (35.1) | 0.000 |
Abdomen | 459 (17.2) | 305 (18.2) | 154 (15.7) | 0.306 |
Skin | 245 (9.2) | 165 (9.8) | 80 (8.2) | 0.239 |
CNS | 68 (2.5) | 47 (2.8) | 21 (2.1) | 0.369 |
Other | 432 (16.1) | 323 (19.3) | 109 (11.1) | 0.000 |
Vital signs* | ||||
Respiratory rate, mean (SD) (590) | 24 (7) | 23 (7) | 26 (7) | 0.158 |
Heart rate, mean (SD) (46) | 108 (20) | 111 (19) | 103 (20) | 0.112 |
MAP, median (IQR) (247) | 94 (83–105) | 94 (84–105) | 94 (84–105) | 0.528 |
Systolic BP, median (IQR) (29) | 130 (115–149) | 129 (115–145) | 135 (115–154) | 0.000 |
Disease severity, median (IQR) | ||||
PIRO score | 10 (6–14) | 8 (4–12) | 13 (9–16) | 0.000 |
Lactate (mmol/L) (286) | 1.8 (1.4–0.6) | 1.80 (1.4–2.5) | 1.90 (1.4–2.7) | 0.023 |
Total amount of fluids received (L) (6) | 1.00 (0.5–1.5) | 1.00 (0.5–1.5) | 1.05 (0.5–1.5) | 0.128 |
Supplemental oxygen (L/min)** (78) | 2 (0–5) | 2 (0–4) | 3 (1–5) | 0.000 |
Mortality, n (%) | 172 (6.5) | 75 (4.5) | 97 (9.9) | 0.000 |