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Table 2 Prevalence of keywords exceeding 20% among ED patients discharged with ICD-10 code sepsis*

From: Keywords reflecting sepsis presentation based on mode of emergency department arrival: a retrospective cross-sectional study

Order

Keyword [5]

Prevalence

P value**

Entire sample of ED patients (N = 479)

EMS group (n = 357)

non-EMS group (n = 122)

Number

Percent (%) and 95% CI

Number

Percent (%) and 95% CI

Number

Percent (%) and 95% CI

1

Abnormal, or suspected abnormal temperature

In turn including primary keywords shivering OR hypothermia OR the following combined keywords: Confirmed or suspected fever, confirmed abnormal temperature (confirmed fever or hypothermia)

319

66.6 (62.3-70.7)

232

65.0 (60.0-69.8)

87

71.3 (62.7-78.6)

0.201

2

Pain

Abdominal/extremity/back/undefined/urinary tract/joint/chest/general/headache/throat/wound/painful muscle cramp/positive Pasternatsy’s sign (costovertebral angle tenderness)

230

48.0 (43.6-52.5)

143

40.1 (35.1-45.2)

87

71.3 (62.7-78.6)

< 0.001

3

Abnormal breathing

Tachypnea, low oxygen saturation, airway secretions, breathing difficulties, cough, or obstructive breathing

210

43.8 (39.5-48.3)

185

51.8 (46.7-57.0)

25

20.5 (14.3-28.5)

< 0.001

4

Risk factors for sepsis

Known ongoing or recent infection, current antibiotic treatment, recent invasive procedures, substance abuse, compromised immune system, chronically compromised breathing

172

35.9 (31.7-40.3)

110

30.8 (26.3-35.8)

62

50.8 (42.1-59.5)

< 0.001

5

Abnormal circulation

Weak pulse or difficulties to palpate the pulse, peripheral coldness, cardiac arrest, tachycardia, low blood pressure, prolonged capillary refill time or non-measurable circulatory variables

163

34.0 (29.9-38.4)

137

38.4 (33.5-43.5)

26

21.3 (15.0-29.4)

0.001

6

Temporal deterioration

Stated deterioration or expressions describing a temporal change

144

30.1 (26.1--34.3)

102

28.6 (24.1-33.5)

42

34.4 (26.6-43.2)

0.223

7

Gastrointestinal symptoms

Vomiting, diarrhea, reduced amount of stool, gastrointestinal bleeding, obstipation, pale feces

137

28.6 (24.7-32.8)

104

29.1 (24.7-34.1)

33

27.0 (20.0-35.5)

0.660

8

Acute altered mental status

Abnormal behavior or level of consciousness (excluding previously known dementia or mental retardation without statement worse) OR abnormal verbal response defined as no/decreased verbal response

127

26.5 (22.8-30.6)

111

31.1 (26.5-36.1)

16

13.1 (8.2-20.2)

< 0.001

9

Abnormal skin

Paleness, wounds or wound infection, sweaty, cyanosis, redness, icterus, mottling, bruises, rash, blisters, or peteckiae, change of skin turgor, exuding skin

125

26.1 (22.4-30.2)

96

26.9 (22.6-31.7)

29

23.8 (17.1-32.1)

0.498

10

Abnormal urination

Abnormal urination (such as hematuria without trauma, bad smelling or cloudy urine, increased frequency of urination) OR urinary tract pain OR decreased urinary volumes OR dysfunction of urinary catheters defined as obstruction/leakage/problematic urinary catheters including nefrostomias

118

24.6 (21.0-28.7)

92

25.8 (21.5-30.6)

26

21.3 (15.0-29.4)

0.324

11

Loss of energy

Defined as fatigue, weakness, faintness or similar expressions

113

23.6 (20.0-27.6)

91

25.5 (21.3-30.3)

22

18.0 (12.2-25.8)

0.094

12

Decreased mobility

in turn including primary keywords remained sitting or lying in an abnormal way OR decreased miscellaneous mobility OR the following combined keywords: “weakness of the legs” and “fallen or being found on the floor”

106

22.1 (18.6-26.1)

93

26.1 (21.8-30.8)

13

10.7 (6.3-17.4)

<  0.001

  1. ED emergency department, EMS emergency medical services, CI confidence interval
  2. *The prevalence of all keywords (both primary and combined) exceeding 20% in the entire sample of patients admitted to the ED of Södersjukhuset during 2013 and discharged with an ICD-10 code compatible with sepsis. The table illustrates the prevalence in the entire group and the prevalence based on mode of arrival
  3. **For comparison between EMS and non-EMS groups. P values are presented without adjustment for multiple comparisons. In total 13 tests were performed. Bonferroni-adjusted significance level is 0,05/13 = 0,0038. P values indicating significant differences after adjustment for multiple comparisons by Bonferroni correction are bolded and considered significant in the current study