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Table 2 Sex differences in baseline characteristic, interventions, and outcome

From: Predictors of neurological outcome after out-of-hospital cardiac arrest: sex-based analysis: do males derive greater benefit from hypothermia management than females?

Study variables

Total

22.416

Females

8109 (36.2%)

Males

14,307 (63.8%)

P value

EMS arrival time, median (IQR)

5.5 (4.2–6.9)

5.4 (4.1–6.7)

5.6 (5.3–6.9)

0.08

Age, median (IQR)

69 (57–81)

71 (57–82)

68 (55–79)

<0.001

Arrest location

 Nonpublic

19,167 (85.8%)

7293 (89.9%)

11,874 (83.0%)

<0.001

 Public

3249 (14.2%)

816 (10.1%)

2433 (17.0%)

 

Bystander witness

 Unwitnessed

12,845 (57.3%)

4946 (61.0%)

7899 (55.2%)

0.001

 Witnessed

9571 (42.7%)

3163 (39.0%)

6408 (44.8%)

 

Bystander CPR

 No

12,013 (53.6%)

4688 (57.8%)

7325 (51.2%)

< 0.001

 Yes

10,403 (46.4%)

3421 (42.2%)

6982 (48.8%)

 

Initial rhythm

 Nonshockable

17,229 (76.9%)

6966 (85.9%)

10,263 (71.7%)

< 0.001

 Shockable

5187 (23.1%)

1143 (14.1%)

4044 (28.3%)

 

Advanced airway

 No

4958 (22.1%)

1810 (22.3%)

3148 (22.0%)

0.80

 Yes

17,458 (77.9%)

6299 (77.7%)

11,159 (78.0%)

 

Administration of epinephrine

 No

3950 (17.6%)

1546 (19.1%)

2404 (16.8%)

 

 Yes

18,466 (82.4%)

6563 (80.9%)

11,903 (83.2%)

0.03

Hypothermia management

 No

18,906 (84.3%)

7031 (86.7%)

11,875 (83.0%)

 

 Yes

3510 (15.7%)

1078 (13.3%)

2432 (17.0%)

< 0.001

Survival outcomes

Hospital discharge

 No

20,471 (91.3%)

7623 (94.0%)

12,848 (89.8%)

< 0.001

 Yes

1945 (8.7%)

486 (6.0%)

1459 (10.2%)

 

Neurological outcomes

 Unfavorable

20,778 (92.7%)

7714 (95.1%)

13,064 (91.4%)

< 0.001

 Favorable

1638 (7.3%)

395 (4.9%)

1243 (8.6%)

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