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Table 3 Multivariate analyses of factors associated with mortality in all patients and the elderly versus non-elderly

From: Clinical factors associated with adverse clinical outcomes in elderly versus non-elderly COVID-19 emergency patients: a multi-center observational study

Factors

All patients

(aOR, 95%CI)

p-value

Non-elderly

(aOR, 95%CI)

p-value

Elderly

(aOR, 95%CI)

p-value

Center

-

0.046

-

0.007

-

0.091

 Siriraj Hospital

Reference

-

Reference

-

Reference

-

 Banphaeo General Hospital

3.07 (0.0-303.0)

0.632

0.00 (0.0-0.0)

1.000

0.00 (0.0-0.0)

0.999

 Ratchaburi Hospital

13.46 (1.9-95.4)

0.009

8.38 (2.3-30.0)

0.001

9.61 (1.3-72.7)

0.028

 Prachuap Kiri Khan Hospital

3.31 (0.6-18.5)

0.174

4.26 (1.1-17.0)

0.040

-a

-a

 Buddhachinaraj Hospital

-a

-a

0.88 (0.1-8.1)

0.908

-a

-a

Age

1.06 (1.0-1.1)

0.001

n/a

n/a

1.13 (1.1-1.2)

<0.001

Male sex

2.50 (1.0-6.1)

0.043

n/a

n/a

3.64 (1.5-8.8)

0.004

Do-not-resuscitate status

6.14 (1.4-27.2)

0.017

34.34 (5.9-200.2)

<0.001

12.46 (3.8-40.7)

<0.001

Charlson comorbidity index

n/a

n/a

1.26 (1.1-1.5)

0.004

n/a

n/a

Systolic blood pressure

1.02 (1.0-1.0)

0.037

n/a

n/a

n/a

n/a

Diastolic blood pressure

0.95 (0.9-1.0)

0.029

n/a

n/a

0.96 (0.9-1.0)

0.002

Body temperature

n/a

n/a

n/a

n/a

1.74 (1.0-2.9)

0.036

Oxygen saturation

n/a

n/a

0.95 (0.9-1.0)

0.006

n/a

n/a

Glasgow Coma Scale score

0.79 (0.6-1.0)

0.074

0.74 (0.6-0.9)

0.016

0.71 (0.5-1.0)

0.026

Platelet

1.0 (1.0-1.0)

0.014

n/a

n/a

n/a

n/a

Glomerular filtration rate

0.98 (1.0-1.0)

0.034

n/a

n/a

n/a

n/a

Lactate

1.68 (1.2-2.4)

0.003

n/a

n/a

n/a

n/a

C-reactive protein

n/a

n/a

n/a

n/a

1.01 (1.0-1.0)

0.006

Procalcitonin

n/a

n/a

1.03 (1.0-1.1)

0.085

n/a

n/a

Total bilirubin

n/a

n/a

1.51 (1.1-2.1)

0.016

0.34 (0.1-0.9)

0.035

Alanine aminotransferase

n/a

n/a

0.99 (1.0-1.0)

0.308

n/a

n/a

Renal replacement therapy

0.13 (0.0-0.8)

0.030

n/a

n/a

n/a

n/a

High flow nasal cannula

n/a

n/a

2.14 (0.8-5.7)

0.131

n/a

n/a

Intubation

7.80 (1.0-58.0)

0.045

n/a

n/a

n/a

n/a

Hospital associated pneumonia

4.37 (1.6-11.7)

0.003

n/a

n/a

n/a

n/a

Septic shock

10.20 (3.0-34.0)

<0.001

n/a

n/a

n/a

n/a

Acute respiratory distress syndrome

36.04 (8.8-148.4)

<0.001

n/a

n/a

n/a

n/a

Pulmonary embolism

0.08 (0.0-0.8)

0.031

n/a

n/a

n/a

n/a

Pneumothorax

0.10 (0.0-1.1)

0.056

n/a

n/a

n/a

n/a

ICU admission

0.03 (0.0-0.2)

<0.001

n/a

n/a

n/a

n/a

  1. Variables included in the model were study center, age, sex, body mass index, day of symptoms, Charlson comorbidity index, do-not-resuscitate status, body temperature, systolic blood pressure, diastolic blood pressure, pulse rate, respiratory rate, oxygen saturation, Glasgow Coma Scale score, hemoglobin, white blood cells, platelet, glomerular filtration rate, D-dimer, lactate, C-reactive protein, total bilirubin, aspartate transaminase, alanine aminotransferase, procalcitonin, high-flow nasal cannula, steroid, favipiravir, remdesivir, tocilizumab, baricitinib, extracorporeal membrane oxygenation, inotropic drugs, renal replacement therapy, ICU admission, and complications
  2. aOR adjusted odds ratio, CI confidence interval, ICU intensive care unit
  3. aInadequate sample size