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Table 1 Time course of blood chemistries and coagulative parameters. In case of repeated measurements, the worst values for each day are reported

From: Waterhouse-Friderichsen syndrome following a dog bite in an asplenic patient: case report and review of the literature

Variables

RV

D1 (admission)

D2a

D3a

D4a

Hb (g/dl)

12–16

10.8

8.6

8.3

9.2

RBC (a106/ml)

4.2–5.0

3.44

2,750

2,650

4,920

WBC (a103/ml)

4.0–11.0

1.90

15.4

32.65

55.60

Platelets (a103/ml)

150–450

8.0

14.2

15.1

8.0

INR

0.78–1.20

Nc

7.23

3.79

4.03

APTTr

0.76–1.18

Nc

2.5

3.95

3.94

Fibrinogen (mg/dl)

180–360

118

68

120

109

Antithrombin III (%)

70–110

25

13

27

23

D-dimer (ng/ml FEU)

 < 500

42.946

112.057

126.574

102.117

pH

7.38–7.42

7.06

7.12

7.25

7.13

HCO3 − (mEq/l)

23–25

8.9

12.3

21.0

20.7

Glycemia (mg/dl)

65–110

54

122

118

86

Tryglicerides (mg/dl)

 < 170

96

Na

Na

300

Lactate (mg/dl)

6.5–19.3

191

157

127

106

Creatinine (mg/dl)

0.4–1.1

2.61

2.21

1.73

1.68

BUN (mg/dl)

15–50

134

41

38

40

Creatin kinase (U/l)

25–195

Na

525

7713

15,400

AST/ALT (U/l)

 < 35/ < 35

3193/2278

7956/4308

11,197/5089

7308/4194

NH4 + (µg/dl)

27–90

200

279

533

817

Total bilirubin (mg/dl)

0.30–1.20

2.71

2.36

3.02

3.05

Ferritin (µg/l)

10–280

3773

Na

Na

 > 7500

Procalcitonin µg/l

 < 0.5

Na

28.56

14.77

7.13

PCR (mg/l)

 < 5

141

51.3

75

112

  1. Legend: RV range values, nc not coagulable, na not available, INR international normalized ratio, APTT activated plasma thromboplastin time ratio
  2. aDuring CVVHD and HA