Table 1 Comparison of background characteristics and clinical courses between the intubation and non-intubation groups
Total (n = 101) | Intubation (n = 33) | Non-intubation (n = 68) | P-value | |
|---|---|---|---|---|
Background (admission) | ||||
Age, years | 58.5 ± 16.7 | 58.9 ± 12.0 | 58.3 ± 18.7 | 0.125 |
Sex, male | 69 (68%) | 24 (73%) | 45 (66%) | 0.513 |
Cigarette smoking | 54 (54%) | 19 (58%) | 35 (52%) | 0.735 |
BMI, kg/m2 | 25.0 ± 4.4 | 25.9 ± 3.9 | 24.5 ± 4.6 | 0.082 |
Comorbidities | ||||
Hypertension | 35 (35%) | 15 (46%) | 20 (29%) | 0.513 |
Diabetes | 24 (24%) | 13 (39%) | 11 (16%) | 0.122 |
COPD | 9 (9%) | 4 (12%) | 5 (7%) | 0.782 |
Cardiovascular disease | 9 (9%) | 2 (6%) | 7 (10%) | 0.182 |
Renal failure | 12 (12%) | 5 (15%) | 7 (10%) | 0.739 |
Cancer | 11 (11%) | 3 (9%) | 8 (12%) | 0.157 |
Laboratory (admission) | ||||
LDH, IU/L | 369.9 ± 166.5 | 486.5 ± 196.5 | 313.3 ± 113.8 | < 0.01 |
CRP, mg/dL | 6.0 ± 4.9 | 8.6 ± 6.2 | 4.7 ± 3.6 | 0.130 |
Lymphocyte, % | 15.7 ± 8.1 | 10.6 ± 5.7 | 18.2 ± 8.0 | < 0.01 |
BNP, pg/mL | 28.7 ± 38.2 | 34.4 ± 35.1 | 26.0 ± 39.6 | 0.797 |
Ferritin, ng/mL | 694.3 ± 492.7 | 1076.0 ± 506.5 | 500.6 ± 355.5 | < 0.01 |
KL-6, U/mL | 356.5 ± 166.5 | 453.2 ± 306.8 | 311.2 ± 185.5 | 0.113 |
d-dimer, μg/mL | 1.9 ± 2.9 | 3.0 ± 4.7 | 1.3 ± 1.0 | 0.052 |
Image (admission) | ||||
CTSS | 6.5 ± 3.4 | 9.8 ± 2.9 | 4.9 ± 2.4 | < 0.01 |
One-time chair stand test (admission) | ||||
Resting SpO2, % | 94.6 ± 2.1 | 93.3 ± 2.6 | 95.2 ± 1.4 | 0.072 |
Lowest SpO2, % | 86.5 ± 9.8 | 80.1 ± 14.6 | 89.7 ± 3.3 | < 0.01 |
ΔSpO2, % | 7.3 ± 3.4 | 10.8 ± 2.4 | 5.5 ± 2.3 | < 0.01 |
Outcome after admission | ||||
Hospitalization, day | 23.8 ± 12.9 | 35.6 ± 13.7 | 18.1 ± 7.6 | < 0.01 |
Return to home | 81 (80%) | 22 (67%) | 59 (87%) | 0.113 |