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Table 4 Results of the multivariate logistic regression analysis

From: Factors associated with non-invasive positive pressure ventilation failure in a COVID-19 intermediate care unit

 

OR

(95% CI)

p value

Age

0.996

(0.931–1.065)

0.905

Frailty score

0.412

(0.141–1.010)

0.105

Highest LDH

1.005

(1.000–1.010)

0.045

Highest CRP

1.164

(1.036–1.308)

0.011

Highest leukocyte count

1.102

(0.925–1.312)

0.277

Lowest platelet count

0.977

(0.960–0.994)

0.010

SpO2 after starting NIPPV

0.839

(0.562–1.251)

0.388

Highest IPAP

0.711

(0.424–1.495)

0.198

Highest EPAP/CPAP

2.636

(0.962–7.220)

0.059

Highest respiratory rate

1.006

(0.863–1.172)

0.940

Remdesivir

0.801

(0.170–3.765)

0.778

Antibiotics

0.864

(0.168–4.434)

0.861

Morphine

24.771

(1.809–339.241)

0.016

Sedationa

3.974

(0.539–29.302)

0.176

Adherence to prone positioning

0.109

(0.017–0.700)

0.020

  1. CPAP continuous positive airway pressure, CRP C-reactive protein, EPAP expiratory positive airway pressure, IPAP inspiratory positive airway pressure, LDH lactate dehydrogenase, NIPPV non-invasive positive pressure ventilation, SpO2 oxygen saturation
  2. aOther than morphine (benzodiazepines. antipsychotics)