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Table 2 Study risk of bias

From: Screening for harmful substance use in emergency departments: a systematic review

Author, Year

Patient Selection

Index Test

Reference standard

Flow & timing

Could the selection of patients have introduced bias?

Could the conduct or interpretation of the index test have introduced bias?

Could the reference standard, its conduct, or its interpretation have introduced bias?

Could the patient flow have introduced bias?

Bastiaens, 2002 [22]

Unclear

Yes

Yes

Unclear

Beaudoin, 2016 [23]

Low

Yes

Unclear

Yes

Borges, 2001 [24]

Low

Unclear

Unclear

Unclear

Brousse, 2014 [25]

Unclear

Yes

Unclear

Unclear

Canagasaby, 2005 [26]

High

Unclear

Unclear

Yes

Chalmers, 2019 [27]

Unclear

Unclear

Unclear

Yes

Cherpitel, 2000a [19]

Low

No

Unclear

No

Cherpitel, 2000b [18]

Low

Yes

Unclear

No

Cherpitel, 2000c [20]

Low

No

Unclear

No

Cherpitel, 2001a [21]

Low

No

Unclear

No

Cherpitel, 2001b [17]

Unclear

No

Unclear

No

Cherpitel, 2003 [28]

Low

No

No

No

Cherpitel, 2005 [29]

Unclear

Yes

Unclear

No

Cremonte, 2010 [30]

Low

Unclear

Unclear

No

Cremonte, 2008 [31]

Low

Unclear

Unclear

Yes

Friedmann, 2001 [32]

Low

No

Unclear

No

Galicia, 2016 [33]

Low

Yes

Unclear

Yes

Geneste, 2012 [34]

Unclear

Yes

Unclear

Yes

Giguere, 2017 [35]

Unclear

Yes

Unclear

Yes

Kelly, 2004 [36]

High

Yes

Unclear

No

Kelly, 2009 [37]

High

Yes

Unclear

No

Lee, 2019 [38]

Unclear

Yes

Yes

No

Meneses-Gaya, 2010a [39]

Low

Yes

Unclear

Yes

Meneses-Gaya, 2010b [40]

Unclear

Yes

Unclear

Yes

Neumann, 2004 [41]

Low

Yes

Unclear

Yes

Neumann, 2009 [42]

High

Yes

Yes

Yes

Sattler, 2019 [43]

Unclear

Unclear

Yes

Yes

Seale, 2018 [44]

Unclear

No

Unclear

No

Singh, 2015 [45]

High

Yes

Yes

Yes

van der Westhuizen, 2016 [46]

Unclear

Yes

Unclear

Yes

Vinson, 2007 [47]

Unclear

Yes

No

No

Williams, 2001 [48]

High

Yes

Unclear

No

Wilson, 2020 [49]

High

No

Unclear

Yes