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Table 2 Association of quantitative variables with QTc intervals over 480 msec at 60 min following ondansetron administration

From: Single intravenous dose ondansetron induces QT prolongation in adult emergency department patients: a prospective observational study

 

Age

(years)

HR

(beats/min)

SBP

(mmHg)

QT0

(msec)

QTc0

(msec)

Total

QTc60 ≤ 480 msec

49.2 (16.9)*

93.9 (13.5)

125.3 (18.4)

328.8 (27.3)

408.8 (24.4)

QTc60 > 480 msec

46.1 (12.4)

93.7 (9.6)

120.2 (11.3)

343.8 (18.4)

424.6 (20.7)

P value

0.46

0.71

0.24

0.03**

0.01**

  1. HR: Initial heart rate, SBP: Initial systolic blood pressure, QTc 0: QTc interval before the administration of ondansetron
  2. *All values are shown in mean (SD)
  3. **Statistical significance